Prescription drugs: injection of pharmaceutical preparations also poses a risk for the development of abscesses. A street cocktail is usually made using injection buprenorphine or pentazocine (Fortwin) mixed with either a benzodiazepine (e.g. Diazepam), pheniraminemaleate(Avil) or promethazine (Phenergan). Pentazocine is notorious for causing abscess when used through the injection route. It can cause cutaneous changes such as erythema, deep or superficial ulcers at or near the injection sites, pigmented halos around the ulcers, bruising, woody induration, edema of the legs and cellulitis. Patients may also develop fibrous myopathy and
limb contractures upon repeated use of pentazocine injections. Repeated use of these chemicals leads to irritation to the veins. An IDU may use these combinations two to four times a day, which results in irritation to the veins resulting in abscess formation.
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